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Roadmap to Nootropics--Part 3: The Best Nootropic Ingredients

by Carol Maser October 21, 2016

Roadmap to Nootropics--Part 3:  The Best Nootropic Ingredients

There are many articles about which nootropic ingredients are the most essential. Like a weight loss product, it is key to look for ingredients that work together to produce a better result than just one of the ingredients alone. If the formula does not have synergistic stacking, then it is essential to look for how much of each ingredient is being used. Is just enough of the ingredient being added to be listed on the label or will you actually receive a benefit from the ingredient?

Oh yeah, also look to see if the product uses branded (trademarked) ingredients that are backed by science versus off-the-shelf ingredients that are usually purchased for the lowest price. A branded ingredient is always consistent in its quality, efficacy and purity. Some ingredients are not branded and that is still okay, as long as the ingredient comes from a reputable global supplier. Global suppliers have the best opportunity when purchasing botanicals and other plant-based ingredients from the same grower, using the same plants and/or the same land to achieve the same ingredient consistency year-after-year.

Synthetic ingredients are sometimes thought of as less-than or not good. However, some of the best nootropic ingredients are synthetic. So having an all-natural label in this case does not mean best. Of course, an ingredient is only BEST if it matches what you are looking for it to do. Do you want an ingredient that crosses the blood brain barrier? If so, why?

Vinpocetine (a semisynthetic) is reported to have cerebral blood-flow enhancing and neuroprotective effects, and is classified and used as a drug product in Eastern Europe for the treatment of cerebrovascular disorders and age-related memory impairment according to Wikipedia.

Noopept (a complete synthetic) is absorbed, circulates to the brain and crosses the blood-brain barrier and has a very high bioavailability level. The substance is one of the fastest-acting nootropic supplements available. Noopept (which is a peptide chemical compound) then travels to specific Glutamate receptor sites within the brain to bind with these sites and help to inhibit the breakdown of Glutamate, one of the most powerful neurotransmitters relative to cognitive function.

There are some synthetic ingredients, though, to stay away from. Not because they are bad for you, but because they do not work with your body as well as the natural form. Vitamin E is the best example for this. Vitamin E has a natural version ( d -alpha-Tocopheryl) and a synthetic version ( dl -alpha-Tocopheryl). The natural version will be absorbed easier and less is needed to achieve the desired result. You expect your vitamins, minerals, and nutrients to be absorbed, which is the reason you spend money on supplements. Not knowing how the ingredient will interact with you once ingested can be a pitfall.

Even some commonly known forms of vitamins are not as good as others. We will “talk” about that in a minute (depending on how fast you read).

So that is what a nootropic ingredient is all about: fuel for your brain. And, it is essential to ensure those ingredients are being used effectively.  How can you make sure you are getting the full benefits from nootropics?  Follow along in part 4 of our Roadmap to Nootropic blog series:  Absorption:  The First Essential.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. CAUTION: Do not take if you are pregnant, nursing, under 16 or with alcohol. If you are taking medication and/or have a medical condition, consult your physician before use.

Carol Maser
Carol Maser


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